Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0003rdr6 | Maternal-Embryo Interactions | REDR1994

Interactions between the immune system and the ruminant conceptus

Hansen PJ

Interactions of the conceptus with the immune system can involve either anti-sperm or anti-conceptus immune responses that limit the success of pregnancy or beneficial effects of cytokines released from lymphoid cells on embryonic growth and gene expression. The immune system is functional in the uterus and therefore there is the potential for anti-conceptus immune responses. However, endometrial lymphocytes are distinct in many respects from lymphoid cells at peripheral sites...

bp0002rdr4 | Maternal Recognition of Pregnancy | REDR1990

Physiological mechanisms of pregnancy recognition in ruminants

Bazer FW , Thatcher WW , Hansen PJ , Mirando MA , Ott TL , Plante C

Summary. Maternal recognition of pregnancy in sheep, cattle and goats involves physiological mechanisms that result in protection of corpora lutea from luteolysis by modification or inhibition of uterine production of luteolytic pulses of prostaglandin (PG) F-2α. Ovine, bovine and caprine luteal cells release oxytocin in a pulsatile manner during late dioestrus. Oxytocin then binds to its endometrial receptors and initiates luteolytic pulses of PGF-2&#945...